Mastering HPLC Troubleshooting: Identifying and Fixing Common Issues

High-Performance Liquid Chromatography (HPLC) is an indispensable tool in analytical chemistry, but even experienced users encounter problems that can affect the quality and reliability of their results. This article delves into the most frequent HPLC issues, their underlying causes, and comprehensive strategies for resolution. 1.Moving Peaks (Variations in Retention Time) Same Column and Same Sample…

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